Searchable abstracts of presentations at key conferences in endocrinology

ea0011p250 | Cytokines and growth factors | ECE2006

Expression of functional toll-like receptors in adipocytes

Oeff KM , Bornstein SR

Various proinflammatory cytokines have been demonstrated to be involved in insulin resistance and other obesity related diseases. Preadipocytes and adipocytes are likely to modulate inflammatory and immune processes by intrinsic mechanisms. Toll-like receptors (TLRs) which are – together with CD14 – involved in the innate immunity and are able to recognize microbial components. Microbial components and immunosuppressive drugs modulate the cytokine expression. We addr...